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SIGMA-1 EUROPE logo
COST Action CA23156 logos developed by elaboranext
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SIGMA-1 EUROPE PowerPoint template
PowerPoint template for SIGMA-1 EUROPE dissemination activities - Version 1
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Short Term Scientific Missions (Call CLOSED)
Open Call for Short-Term Scientific Missions: 20 March 2025 – 30 September 2025
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Young Researcher and Innovator Conference Grants (Call CLOSED)
Open Call for Young Researcher and Innovator Conference Grants: 20 March 2025 – 30 September 2025
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ITC Conference Grants (Call CLOSED)
Open Call for ITC Conference Grants: 20 March 2025 – 30 September 2025
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The 1st SIGMA-1 EUROPE meeting
The Final Program: 25-27 June 2025
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Abstract Book of the 1st SIGMA-1 EUROPE meeting
25-27 June, 2025
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WG3 meeting (Granada, Spain) presentations
Overview of activities/resources available for SIGMA-1 EUROPE members and partners - Introduction of labs/research groups
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WG2 meeting (Nice, France)
Program: 26 September, 2025
Publications
Design and Synthesis of Tetrahydropyrrolo[3,4-c]Pyrazole Sigma-1 Receptor Ligands
Cosentino et al., ChemMedChem 2025
Publications
Two Targets, One Mission: Heterobivalent Metal-Based Radiopharmaceuticals for Prostate Cancer Imaging and Therapy
Sobral et al., ChemMedChem 2025
Publications
Improving mitochondria-associated endoplasmic reticulum membranes integrity as converging therapeutic strategy for rare neurodegenerative diseases and cancer
Cagalinec et al., Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2025
Publications
Sigma-1 receptor antagonism as a promising strategy for postoperative pain treatment: A study in laparotomized mice
Santos-Caballero et al., Biomedicine & Pharmacotherapy 2025
Publications
Generation and phenotypic characterization of a sigma-1 receptor knockout rat
Huerta et al., Life Sciences 2025
Publications
Sigma-1-targeting multimodal compound HBK-15 reverses memory deficits and restores hippocampal plasticity under NMDA hypofunction
Salaciak et al., Neurotherapeutics 2025
Publications
A Full-Spectrum Evaluation of Sigma-1 Receptor (S1R) Positron Emission Tomography (PET) Radioligands from Binding Affinity to Clinical Imaging
Mastropasqua et al., Molecules 2025

What is COST?

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

COST ACTION CA23156

The SIGMA-1 EUROPE Action is dedicated to promoting excellence in research and innovation related to sigma-1 receptor physiopathology and therapeutic applications across multiple fields. This initiative fosters interdisciplinary collaboration to drive breakthrough science and technological advancements in medicinal chemistry and pharmaceutical development.

Action Details

Action Start Date: October 25, 2024
Action End Date: October 24, 2028

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